There has been a recent growth in research investigating the efficacy and safety of a broad spectrum of micronutrients as treatment for mental health symptoms. In this talk, Prof Rucklidge will discuss the rationale for using a broad-spectrum micronutrient (vitamins and minerals) approach to treat challenges from emotional dysregulation to perinatal depression to stress, reviewing when supplementation might be necessary despite a good diet, the hypothesised mechanisms of action and the current clinical evidence alongside side effects and safety.